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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | actin filament associated protein 1 like 2 |
| Gene Symbol: | AFAP1L2 |
| Synonyms: | XB130; KIAA1914; CTB-1144G6.4; AFAP1L2 |
| Gene ID: | 84632 |
| UniProt ID: | Q8N4X5 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 0.58 mg/ml |
| Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-AFAP1L2 antibody |
Background
Enables SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. Located in cytosol and plasma membrane.
Images
 | Western blot analysis of various lysates using AFAP1L2 Rabbit pAb (A15916) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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