AGL Rabbit pAb (20 μl)

AGL Rabbit pAb (20 μl)

Brand: Abclonal
Cat. #: A10051
Availability: In Stock
$108.00
-+
Reactivity: Human, Mouse    
Applications: WB, ELISA    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Polyclonal antibody    
Gene Name: amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
Gene Symbol: AGL
Synonyms: GDE; AGL
Gene ID: 178
UniProt ID: P35573
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1233-1532 of human AGL (NP_000633.2).
Dilution: WB 1:500-1:2000
Purification Method: Affinity purification
Concentration: 0.35 mg/ml
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-AGL antibody




Background

This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.




Images

AGL antibodyWestern blot analysis of various lysates using AGL Rabbit pAb (A10051) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.



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