Reactivity: | Human, Mouse |
Applications: | WB, IF/IC, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | alkylglycerone phosphate synthase |
Gene Symbol: | AGPS |
Synonyms: | ADAS; ADPS; RCDP3; ADAP-S; ADHAPS; ALDHPSY; AGPS |
Gene ID: | 8540 |
UniProt ID: | O00116 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 379-658 of human AGPS (NP_003650.1). |
Dilution: | WB 1:1000-1:2000; IF/IC 1:50-1:200 |
Purification Method: | Affinity purification |
Concentration: | 3.66 mg/ml |
Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-AGPS antibody |
Background
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.
Images
![]() | Western blot analysis of various lysates using AGPS Rabbit pAb (A10484) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
![]() | Immunofluorescence analysis of U2OS cells using AGPS Rabbit pAb (A10484) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining. |
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