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Anti-AP3B2 Rabbit pAb (100 μl)
| Reactivity: | M,R & M |
| Applications: | IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | AP-3 complex subunit beta-2 |
Synonyms: | AP 3 complex subunit beta 2, Beta 3B adaptin, NAPTB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AP3B2 |
Uniprot ID: | Q9JME5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 800-1: 2400 | colon, kidney, stomach, brain |
ICC/IF | Mouse | 1: 100-1: 400 | NIH-3T3 |
Background
Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Images
| Immunohistochemistry analysis of paraffin embedded rat colon using AP3B2 (GB114993) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse kidney using AP3B2 (GB114993) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat brain using AP3B2 (GB114993) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse colon using AP3B2 (GB114993) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat stomach using AP3B2 (GB114993) at dilution of 1: 800 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using AP3B2 (GB114993) at dilution of 1: 200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |