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APC/Cyanine7 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb (100 T)
| Reactivity: | Human,Monkey |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | APC-Cy7. Ex:651nm. Em:779nm. |
| Gene Name: | interleukin 7 receptor |
| Gene Symbol: | IL7R |
| Synonyms: | ILRA; CD127; IL7RA; CDW127; IMD104; sIL-7R; lnc-IL7R; IL7Ralpha; IL-7Ralpha; IL-7R-alpha |
| Gene ID: | 3575 |
| UniProt ID: | P16871 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-236 human CD127/IL-7Rα (NP_002176.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-IL7R Antibody |
Background
The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
Images
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with PE Rabbit anti-Human CD3 mAb (A27110,5 μl/Test) and APC/Cyanine7 Rabbit IgG isotype control (5 μl/Test,left) or APC/Cyanine7 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb (A27437,5 μl/Test,right). Cells in the lymphocyte gate were used for analysis. |
 | Flow cytometry: 1×10^6 Monkey PBMC were surface-stained with APC/Cyanine7 Rabbit IgG isotype control (5 μl/Test,left) or APC/Cyanine7 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb (A27437,5 μl/Test,right). Cells in the Lymphocyte gate were used for analysis. |
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