APC Rabbit anti-Human CD10 mAb (100 T)

APC Rabbit anti-Human CD10 mAb (100 T)

Brand: Abclonal
Cat. #: A25935
Availability: In Stock
$218.00
-+
Reactivity: Human    
Applications: FC    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Monoclonal Antibody    
Conjugation: APC. Ex:650nm. Em:660nm.
Gene Name: membrane metalloendopeptidase
Gene Symbol: MME
Synonyms: NEP; SFE; CD10; CALLA; CMT2T; SCA43
Gene ID: 4311
UniProt ID: P08473
Clone ID: 6L1G7
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 52-750 of human CD10 (NP_000893.2).
Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Purification Method: Affinity purification
Concentration: 0.01 mg/ml
Buffer: PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-MME Antibody




Background

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.




Images

MME  AntibodyFlow cytometry: 1×10^6 A549 cells (negative control,left) and Daudi cells (right) were surface-stained with APC Rabbit anti-Human CD10 mAb (A25935,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry: 1×10^6 Daudi cells were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Human CD10 mAb (A25935,5 μl/Test,right).



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