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APC Rabbit anti-Mouse CD124/IL-4Ra mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | APC. Ex:650nm. Em:660nm. |
| Gene Name: | interleukin 4 receptor, alpha |
| Gene Symbol: | Il4ra |
| Synonyms: | Il4r; CD124 |
| Gene ID: | 16190 |
| UniProt ID: | P16382 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-233 of mouse CD124/IL-4Ra (NP_001008700.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Il4ra antibody |
Background
Predicted to enable cytokine receptor activity. Involved in positive regulation of chemokine production; positive regulation of cold-induced thermogenesis; and positive regulation of macrophage activation. Acts upstream of or within several processes, including defense response to protozoan; negative regulation of T-helper 1 cell differentiation; and positive regulation of immune effector process. Predicted to be located in several cellular components, including centriolar satellite; extracellular space; and nucleoplasm. Predicted to be part of receptor complex. Is expressed in several structures, including adrenal medulla; early conceptus; hemolymphoid system; medulla oblongata basal plate mantle layer; and reproductive system. Used to study asthma. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; autoimmune disease (multiple); human immunodeficiency virus infectious disease; and renal tuberculosis. Orthologous to human IL4R (interleukin 4 receptor).
Images
 | Flow cytometry: 1×10^6 293F cells (negative control,left) and 293F (Transfection,right) cells were surface-stained with APC Rabbit anti-Mouse CD124/IL-4Ra mAb (A26538,5 μl/Test,orange line) or APC Rabbit IgG isotype control (A24173,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 293T (Transfection) cells were surface-stained with APC Rabbit IgG isotype control (A24173,5 μl/Test,left) or APC Rabbit anti-Mouse CD124/IL-4Ra mAb (A26538,5 μl/Test,right). |
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