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| Reactivity: | Human |
| Applications: | WB, IF/IC, IP, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | apolipoprotein B mRNA editing enzyme catalytic subunit 3C |
| Gene Symbol: | APOBEC3C |
| Synonyms: | A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3; APOBEC3C |
| Gene ID: | 27350 |
| UniProt ID: | Q9NRW3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human APOBEC3C (NP_055323.2). |
| Dilution: | WB 1:500-1:2000; IF/IC 1:50-1:200 |
| Purification Method: | Affinity purification |
| Concentration: | 2.44 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-APOBEC3C antibody |
Background
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
Images
 | Western blot analysis of lysates from K-562 cells, using APOBEC3C Rabbit pAb (A14510) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunoprecipitation analysis of 200 μg extracts of K-562 cells, using 3 μg APOBEC3C antibody (A14510). Western blot was performed from the immunoprecipitate using APOBEC3C antibody (A14510) at a dilution of 1:1000. |
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