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ABflo® 488 Rabbit anti-Human CD157/BST-1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | bone marrow stromal cell antigen 1 |
| Gene Symbol: | BST1 |
| Synonyms: | CD157; cADPR2 |
| Gene ID: | 683 |
| UniProt ID: | Q10588 |
| Clone ID: | 6J3K7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-292 of human CD157/BST-1 (NP_004325.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-BST1 Antibody |
Background
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
Images
 | Flow cytometry: 1×10^6 MCF7 cells (Low Expression,left) and THP-1 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD157/BST-1 mAb (A25155,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 THP-1 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD157/BST-1 mAb (A25155,5 μl/Test,right). |
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