Reactivity: | Human, Mouse, Rat |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Clonality: | Polyclonal antibody |
Gene Name: | B cell scaffold protein with ankyrin repeats 1 |
Gene Symbol: | BANK1 |
Synonyms: | BANK; BANK1 |
Gene ID: | 55024 |
UniProt ID: | Q8NDB2 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 516-785 of human BANK1 (NP_060405.4). |
Dilution: | WB 1:1000-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 0.64 mg/ml |
Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-BANK1 antibody |
Background
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
Images
![]() | Western blot analysis of various lysates using BANK1 Rabbit pAb (A10312) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
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