Reactivity: | Human, Mouse, Rat |
Applications: | WB, IP, ELISA |
Host Species: | Rabbit |
Clonality: | Monoclonal antibody |
Gene Name: | calcium/calmodulin dependent protein kinase II delta |
Gene Symbol: | CAMK2B |
Synonyms: | CAM2; CAMK2; CAMKB; MRD54; CaMKIIbeta; CaMK2 delta/CAMK2 gamma |
Gene ID: | 817/818 |
UniProt ID: | Q13554 |
Clone ID: | 7L9F0 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CaMK2 delta/CAMK2 gamma (Q13554). |
Dilution: | WB 1:5000-1:12000 |
Purification Method: | Affinity purification |
Concentration: | 1.20 mg/mL |
Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-CAMK2B antibody |
Background
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.
Images
![]() | Western blot analysis of various lysates using CaMK2 delta/CAMK2 gamma Rabbit mAb (A0186) at 1:11000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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