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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Monoclonal antibody |
| Gene Name: | catenin beta interacting protein 1 |
| Gene Symbol: | CTNNBIP1 |
| Synonyms: | ICAT; CTNNBIP1 |
| Gene ID: | 56998 |
| UniProt ID: | Q9NSA3 |
| Clone ID: | 8F7O5 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-81 of human CTNNBIP1 (Q9NSA3). |
| Dilution: | WB 1:500-1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 0.5 mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CTNNBIP1 antibody |
Background
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
Images
 | Western blot analysis of lysates from TE-1 cells, using CTNNBIP1 Rabbit mAb (A0914) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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