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| Reactivity: | Rat |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | exosome component 5 |
| Gene Symbol: | EXOSC5 |
| Synonyms: | p12B; CABAC; RRP46; RRP41B; Rrp46p; hRrp46p; EXOSC5 |
| Gene ID: | 56915 |
| UniProt ID: | Q9NQT4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-235 of human EXOSC5 (NP_064543.3). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.01 mg/ml |
| Buffer: | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-EXOSC5 antibody |
Background
Predicted to enable RNA binding activity. Involved in DNA deamination and exonucleolytic catabolism of deadenylated mRNA. Acts upstream of or within defense response to virus. Located in nucleolus; nucleoplasm; and transcriptionally active chromatin. Part of exosome (RNase complex).
Images
 | Western blot analysis of lysates from rat pancreas, using EXOSC5 Rabbit pAb (A15870) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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