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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Monoclonal antibody |
| Gene Name: | oligodendrocyte transcription factor 3 |
| Gene Symbol: | OLIG3 |
| Synonyms: | Bhlhb7; bHLHe20; Olig3 |
| Gene ID: | 167826 |
| UniProt ID: | Q7RTU3 |
| Clone ID: | 9C1N3 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 173-272 of human Olig3 (Q7RTU3). |
| Dilution: | WB 1:1000-1:6000 |
| Purification Method: | Affinity purification |
| Concentration: | 0.50 mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-OLIG3 antibody |
Background
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II; spinal cord motor neuron cell fate specification; and spinal cord motor neuron migration. Predicted to be part of chromatin. Predicted to be active in nucleus.
Images
 | Western blot analysis of lysates from U-251 MG cells, using Olig3 Rabbit mAb (A0600) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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