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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | CD33 molecule |
| Gene Symbol: | CD33 |
| Synonyms: | p67; SIGLEC3; SIGLEC-3; CD33rSiglec |
| Gene ID: | 945 |
| UniProt ID: | P20138 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-259 of human CD33(NP_001763.3) |
| Dilution: | FC, 5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD33 Antibody |
Background
Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome.
Images
 | Flow cytometry: 1×10^6 MCF7 cells (negative control,left) and THP-1 cells (right) were surface-stained with PE Rabbit anti-Human CD33 mAb (A26825,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 THP-1 cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD33 mAb (A26825,5 μl/Test,right). |
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with PE Rabbit anti-Human CD33 mAb (A26825,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 Human PBMC were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Human CD33 mAb (A26825,5 μl/Test,right). |
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