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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | phospholipase A2 receptor 1 |
| Gene Symbol: | PLA2R1 |
| Synonyms: | PLA2R; PLA2-R; PLA2IR; CLEC13C; PLA2G1R; PLA2R1 |
| Gene ID: | 22925 |
| UniProt ID: | Q13018 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 870-1130 of human PLA2R1 (NP_031392.3). |
| Dilution: | WB 1:500-1:1000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.37 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-PLA2R1 antibody |
Background
This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.
Images
 | Western blot analysis of lysates from A-549 cells, using PLA2R1 Rabbit pAb (A10068) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
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