Reactivity: | Human, Mouse, Rat |
Applications: | WB, IHC, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | solute carrier family 11 member 2 |
Gene Symbol: | SLC11A2 |
Synonyms: | DCT1; DMT1; AHMIO1; NRAMP2; DMT1/SLC11A2 |
Gene ID: | 4891 |
UniProt ID: | P49281 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-63 of human DMT1/SLC11A2 (NP_001167597.1). |
Dilution: | WB 1:1000-1:2000; IHC 1:50-1:200 |
Purification Method: | Affinity purification |
Concentration: | 1.41mg/ml |
Buffer: | PBS with 0.09% Sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-SLC11A2 antibody |
Background
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
![]() | Western blot analysis of various lysates using DMT1/SLC11A2 Rabbit pAb (A10231) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
![]() | Immunohistochemistry analysis of paraffin-embedded Rat stomach using DMT1/SLC11A2 Rabbit pAb (A10231) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M Tris/EDTA Buffer (pH 9.0) prior to IHC staining. |
![]() | Immunohistochemistry analysis of paraffin-embedded Mouse stomach using DMT1/SLC11A2 Rabbit pAb (A10231) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M Tris/EDTA Buffer (pH 9.0) prior to IHC staining. |
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