Reactivity: | Human |
Applications: | WB, ELISA |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Polyclonal antibody |
Gene Name: | trafficking protein particle complex subunit 2 |
Gene Symbol: | TRAPPC2 |
Synonyms: | SEDL; SEDT; MIP2A; TRS20; ZNF547L; hYP38334; TRAPPC2P1; TRAPPC2 |
Gene ID: | 6399 |
UniProt ID: | P0DI81 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TRAPPC2 (NP_055378.1). |
Dilution: | WB 1:500-1:2000 |
Purification Method: | Affinity purification |
Concentration: | 3.16 mg/ml |
Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-TRAPPC2 antibody |
Background
The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene.
Images
![]() | Western blot analysis of various lysates using TRAPPC2 Rabbit pAb (A10465) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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