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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Apolipoprotein E (APOE) under a CMV promoter. |
| Description: | Apolipoprotein E, pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Apolipoprotein E |
| NCBI Acc. #: | BC003557 |
| Gene ID: | 348 |
| GI Number: | 13097698 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1×1010~1×1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | The protein encoded by the APOE gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
| Storage: | -80°C |
| Documents: | Please contact us to request the manual |
