Adenovirus Bmal1 (5×200 μl)

Product Category:

Human Adenovirus expressing rat Bmal1.   

Description:

Pre-made adenovirus for over-expression of rat Bmal1; Ready to ship and ready to use format.

Gene Name:

basic helix-loop-helix ARNT like 1

Gene Symbol:

Bmal1

Synonyms:

Arntl

ACCN:

NM_024362.2

Gene ID:

29657

Vector:

VD030-Max-CMV-MCS-EF1-puro

Fusion Tag:

3×Flag tag

Promoter:

CMV

Selection Antibiotic:

Puromycin

Titer:

≥1E+10PFU/ml

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

The protein encoded by the gene Bmal1 is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns.

Storage:

-80°C

Documents:

Manual