Product Category:
Human Adenovirus expressing mouse Cd44.
Description:
Premade adenovirus for over-expression of mouse Cd44; Ready to ship and ready to use format.
Gene Name:
CD44 antigen
Gene Symbol:
Cd44
Synonyms:
Ly-24; Pgp-1; HERMES
ACCN:
NM_009851.2
Gene ID:
12505
Vector:
VD027-Max-CMV-MCS-EF1-zsgreen-T2A-puro
Fusion Tag:
3×Flag tag
Selection Antibiotic:
Puromycin
Promoter:
CMV
Titer:
≥1E+10PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Enables cargo receptor activity; hyaluronic acid binding activity; and type II transforming growth factor beta receptor binding activity. Contributes to cytokine binding activity and cytokine receptor activity. Involved in several processes, including hyaluronan catabolic process; negative regulation of T cell activation; and regulation of intracellular signal transduction. Acts upstream of or within several processes, including Wnt signaling pathway; morphogenesis of a branching epithelium; and wound healing involved in inflammatory response. Located in basolateral plasma membrane; external side of plasma membrane; and microvillus. Part of macrophage migration inhibitory factor receptor complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and limb. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (IN blood group)).
Storage:
-80°C
Documents: