Product Category:
Human Adenovirus expressing mouse Clec7a.
Description:
Pre-made adenovirus for over-expression of mouse Clec7a; Ready to ship and ready to use format.
Gene Name:
C-type lectin domain family 7, member a
Gene Symbol:
Clec7a
Synonyms:
BGR; beta-GR; Clecsf12
ACCN:
NM_020008.4
Gene ID:
56644
Vector:
VD052-Max-CMV-MCS-EF1-mcherry
Fusion Tag:
3×Flag tag
Promoter:
CMV
Titer:
≥1E+10PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Enables (1->3)-beta-D-glucan binding activity; (1->3)-beta-D-glucan immune receptor activity; and opsonin binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of intracellular signal transduction; and response to fungus. Acts upstream of or within several processes, including phagocytosis; regulation of calcineurin-NFAT signaling cascade; and regulation of gene expression. Located in external side of plasma membrane. Is expressed in several structures, including gut; limb; musculature; spleen; and ventral grey horn. Human ortholog(s) of this gene implicated in aspergillosis and chronic mucocutaneous candidiasis. Orthologous to human CLEC7A (C-type lectin domain containing 7A).
Storage:
-80°C
Documents: