Product Category:
Human Adenovirus expressing mouse Cth.
Description:
Premade adenovirus for over-expression of mouse Cth; Ready to ship and ready to use format.
Gene Name:
cystathionine gamma lyase
Gene Symbol:
Cth
Synonyms:
CGL; CSE; Cys3; 0610010I13Rik
ACCN:
NM_145953.2
Gene ID:
107869
Vector:
VD027-Max-CMV-MCS-EF1-zsgreen-T2A-puro
Fusion Tag:
3×Flag tag
Promoter:
CMV
Selection Antibiotic:
Puromycin
Titer:
≥1E+10PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Enables L-cystine L-cysteine-lyase (deaminating) and cystathionine gamma-lyase activity. Involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of canonical NF-kappaB signal transduction; and protein sulfhydration. Acts upstream of or within cellular response to leukemia inhibitory factor and negative regulation of apoptotic signaling pathway. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; cranium; ear; and genitourinary system. Used to study cystathioninuria. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase).
Storage:
-80°C
Documents: