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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Epidermal Growth Factor Receptor (erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Avian) (EGFR) under a CMV promoter. |
| Description: | Epidermal Growth Factor Receptor (erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Avian), pre-packaged adenovirus, ready to ship and ready to use format. |
| Gene: | Epidermal Growth Factor Receptor (erythroblastic Leukemia Viral (v-erb-b) Oncogene Homolog, Avian) |
| NCBI Acc. #: | U48722 |
| Gene ID: | 1956 |
| GI Number: | 1956 |
| Fusion Tag: | No |
| Promoter: | CMV |
| Titer: | 1x1010~1x1011 PFU/ml |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | EGFR, also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer. |
| Documents: | Please contact us to request the manual |
