Adenovirus ITGB4 (5×200 μl)

Product Category:

Human Adenovirus expressing human ITGB4.   

Description:

Premade adenovirus for over-expression of human ITGB4; Ready to ship and ready to use format.

Gene Name:

integrin subunit beta 4

Gene Symbol:

ITGB4

Synonyms:

CD104; GP150; JEB5A; JEB5B

ACCN:

NM_000213.5

Gene ID:

3691

Vector:

VD030-MAX-CMV-MCS-EF1-puro

Fusion Tag:

3×Flag tag

Promoter:

CMV

Titer:

≥1E+10PFU/ml

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. The gene ITGB4 encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Storage:

-80°C

Documents:

Manual