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| Product Category: | Human Adenovirus Type5 (dE1/E3) expressing Runt-related transcription factor 3 (RUNX3) under CMV promoter. |
| Description: | Runt-related transcription factor 3 (RUNX3), pre-made adenovirus, ready to ship and ready to use format. |
| Gene: | Runt-related transcription factor 3 |
| NCBI Acc. #: | BC013362 |
| Gene ID: | 864 |
| GI Number: | 33878242 |
| Fusion Tag: | V5 tag at C-terminal |
| Promoter: | CMV |
| Storage Buffer: | DMEM with 2.5% BSA, 2.5% glycerol |
| Background: | RUNX3 gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Documents: | Please contact us to request the manual |
