Adenovirus Sting1 (5×200 μl)

Product Category:

Human Adenovirus expressing mouse Sting1.   

Description:

Premade adenovirus for over-expression of mouse Sting1; Ready to ship and ready to use format.

Gene Name:

stimulator of interferon response cGAMP interactor 1

Gene Symbol:

Sting1

Synonyms:

ERIS; MPYS; Mita; STING; Tmem173; STING-beta; 2610307O08Rik

ACCN:

NM_001289591.1

Gene ID:

72512

Vector:

VD053-Max-CMV-MCS

Fusion Tag:

HA tag

Promoter:

CMV

Titer:

≥1E+10PFU/ml

Storage Buffer:

DMEM with 2.5% BSA, 2.5% glycerol

Background:

Enables 2',3'-cyclic GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to symbiont; macroautophagy; and positive regulation of innate immune response. Acts upstream of or within cellular response to interferon-beta; positive regulation of transcription by RNA polymerase II; and regulation of inflammatory response. Located in several cellular components, including Golgi membrane; autophagosome; and perinuclear region of cytoplasm. Part of STING complex. Is active in endoplasmic reticulum membrane and endoplasmic reticulum-Golgi intermediate compartment membrane. Is expressed in ductus deferens; epididymis; ileum; liver; and prostate gland. Used to study STING-associated vasculopathy with onset in infancy. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).

Storage:

-80°C

Documents:

Manual