Adenovirus TPP1 (200 μl)

Adenovirus TPP1 (200 μl)

Cat. #: M1240
Availability: In Stock
$685.00
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Product Category:   Human Adenovirus Type5 (dE1/E3) expressing Tripeptidyl Peptidase I (TPP1).
Description:   Tripeptidyl Peptidase I, pre-made adenovirus, ready to ship and ready to use format.
Gene:   Tripeptidyl Peptidase I
NCBI Acc. #:   BC014863
Gene ID:   1200
GI Number:   15928807
Fusion Tag:   No
Promoter:   CMV
Titer:   1x1010~1x1011 PFU/ml
Storage Buffer:   DMEM with 2.5% BSA, 2.5% glycerol
Background:   The TPP1 gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Documents: Please contact us to request the manual

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