Product Category:
Human Adenovirus expressing mouse Tlr2.
Description:
Premade adenovirus for over-expression of mouse Tlr2; Ready to ship and ready to use format.
Gene Name:
toll-like receptor 2
Gene Symbol:
Tlr2
Synonyms:
Ly105
ACCN:
NM_011905.3
Gene ID:
24088
Vector:
VD051-MAX-CMV-MCS-EF1a-ZsGreen
Fusion Tag:
3×Flag tag
Promoter:
CMV
Titer:
≥1E+10PFU/ml
Storage Buffer:
DMEM with 2.5% BSA, 2.5% glycerol
Background:
Enables several functions, including amyloid-beta binding activity; lipopeptide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including microglia development; negative regulation of cellular component organization; and positive regulation of cytokine production. Acts upstream of or within several processes, including positive regulation of defense response; regulation of cytokine production; and response to bacterium. Located in external side of plasma membrane. Part of Toll-like receptor 2-Toll-like receptor 6 protein complex. Is expressed in several structures, including brain; early embryo; genitourinary system; gut; and immune system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2).
Storage:
-80°C
Documents: