Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Alpha 2 Antiplasmin rabbit polyclonal |
Gene Name: | Alpha-2-antiplasmin |
Synonyms: | A2AP, AAP, Alpha 2 antiplasmin, Alpha 2 AP, ALPHA 2 PI, Alpha 2 plasmin inhibitor, API, PLI, Serpin F2, SERPINF2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Alpha 2 Antiplasmin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 55 kDa |
Observed MW. | 55 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 800 | HepG2, K562, THP-1 |
Background
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
![]() | Western blot analysis of A2AP (GB113165) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |