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ABflo® 450 Rabbit anti-Mouse CD127/IL-7Rα mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 450. Ex:406nm. Em:445nm. |
| Gene Name: | interleukin 7 receptor |
| Gene Symbol: | Il7r |
| Synonyms: | CD127; IL-7Ralpha |
| Gene ID: | 16197 |
| UniProt ID: | P16872 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of mouse CD127/IL-7Rα(NP_612564.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Il7r antibody |
Background
Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules.
Images
 | Flow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with ABflo® 450 Rabbit anti-Mouse CD127/IL-7Rα mAb (A26545,5 μl/Test,orange line) or ABflo® 450 Rabbit IgG isotype control (5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 293T (Transfection) cells were surface-stained with ABflo® 450 Rabbit IgG isotype control (5 μl/Test,left) or ABflo® 450 Rabbit anti-Mouse CD127/IL-7Rα mAb (A26545,5 μl/Test,right). |
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