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ABflo® 488 Anti-Mouse CD11c mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Armenian Hamster |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | integrin alpha X |
| Gene Symbol: | Itgax |
| Synonyms: | Cr4; N418; Cd11c |
| Gene ID: | 16411 |
| UniProt ID: | Q9QXH4 |
| Immunogen: | Recombinant protein of mouse CD11c . |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Itgax antibody |
Background
Predicted to enable receptor tyrosine kinase binding activity. Involved in positive regulation of gene expression and positive regulation of myelination. Acts upstream of or within defense response to virus. Located in external side of plasma membrane. Is expressed in heart and hemolymphoid system. Orthologous to human ITGAX (integrin subunit alpha X).
Images
 | Flow cytometry: 1×10^6 NIH/3T3 cells (negative control,left) and C57BL/6 mouse splenocytes (right) cells were surface-stained with ABflo® 488 Anti-Mouse CD11c mAb (A27436,5 μl/Test,orange line) or ABflo® 488 Armenian Hamster IgG (5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 C57BL/6 mouse splenocytes were surface-stained with FITC anti-Mouse/Human CD45R/B220 mAb (A25655,5 μl/Test) and ABflo® 488 Armenian Hamster IgG (5 μl/Test,left) or ABflo® 488 Anti-Mouse CD11c mAb (A27436,5 μl/Test,right). Cells in lymphocyte and monocyte gates were used for analysis. |
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