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ABflo® 488 Rabbit anti-Human CD303/BDCA-2 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | C-type lectin domain family 4 member C |
| Gene Symbol: | CLEC4C |
| Synonyms: | DLEC; HECL; BDCA2; CD303; BDCA-2; CLECSF7; CLECSF11; PRO34150 |
| Gene ID: | 170482 |
| UniProt ID: | Q8WTT0 |
| Clone ID: | 8M4V10 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 45-213 of human CD303/BDCA-2 (NP_569708.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CLEC4C antibody |
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Images
 | Flow cytometry: 1×10^6 293F cells (negative control,left) and 293F (Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Human CD303/BDCA-2 mAb (A24311,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 488 Rabbit anti-Human CD303/BDCA-2 mAb (A24311,5 μl/Test,right) and ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or PE anti-Human CD123 mAb (5 μl/Test,right). Cells in the lymphocytes and monocytes gate were used for analysis. |
 | Flow cytometry: 1×10^6 293F (Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD303/BDCA-2 mAb (A24311,5 μl/Test,right). |
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