ABflo® 488 Rabbit anti-Human CD62L/L-Selectin mAb (100 T)

Brand: Abclonal
Cat. #: A23020
Availability: In Stock

$290.00

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Description

Reactivity:	Human
Applications:	FC
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal Antibody
Conjugation:	ABflo® 488. Ex:491nm. Em:516nm.
Gene Name:	selectin L
Gene Symbol:	SELL
Synonyms:	TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
Gene ID:	6402
UniProt ID:	P14151
Clone ID:	5P0V1
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 39-332 of human CD62L/L-Selectin (NP_000646.3).
Dilution:	FC,5 μl per 10^6 cells in 100 μl volume
Purification Method:	Affinity purification
Concentration:	0.04 mg/mL
Buffer:	PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage:	Store at -20°C. Avoid freeze / thaw cycles.
Documents:	Manual-SELL Antibody

Background

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Images

	Flow cytometry:1×10^6 T-47D cells (negative control,Left) and MOLT-4 cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human CD62L/L-Selectin mAb(A23020,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells was used as blank control (red line).
	Flow cytometry:1×10^6 MOLT-4 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD62L/L-Selectin mAb(A23020,5 μl/Test,right).