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ABflo® 488 Rabbit anti-Human CD70 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | CD70 molecule |
| Gene Symbol: | CD70 |
| Synonyms: | CD27L; LPFS3; CD27-L; CD27LG; TNFSF7; TNLG8A |
| Gene ID: | 970 |
| UniProt ID: | P32970 |
| Clone ID: | 10E5Z9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-193 of human CD70 (P32970). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CD70 Antibody |
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Images
 | Flow cytometry: 1×10^6 293F cells (negative control,left) and Raji cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD70 mAb (A22302,2 μg/mL,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,2 μg/mL,blue line). Non-fluorescently stained cells was used as blank control (red line). |
 | Flow cytometry: 1×10^6 Raji cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CD70 mAb (A22302,5 μl/Test,right). |
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