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| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | CUB domain containing protein 1 |
| Gene Symbol: | CDCP1 |
| Synonyms: | CD318; TRASK; SIMA135 |
| Gene ID: | 64866 |
| UniProt ID: | Q9H5V8 |
| Clone ID: | 5X6M4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-666 of human CDCP1 (NP_073753.3). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CDCP1 antibody |
Background
This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene.
Images
![]() | Flow cytometry: 1×10^6 HEL cells (negative control,left) and PC-3 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CDCP1 mAb (A22498,2 μg/mL,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,2 μg/mL,blue line). Non-fluorescently stained cells was used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 PC-3 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CDCP1 mAb (A22498,5 μl/Test,right). |
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