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ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | C-type lectin domain family 12 member A |
| Gene Symbol: | CLEC12A |
| Synonyms: | CLL1; MICL; CD371; CLL-1; DCAL-2; hKLRL1 |
| Gene ID: | 160364 |
| UniProt ID: | Q5QGZ9-2 |
| Clone ID: | 9V5N6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 65-265 of human CLEC12A/CD371 (NP_612210.4). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-CLEC12A antibody |
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.
Images
 | Flow cytometry:1×10^6 K-562 cells (negative control,Left) and U-937 cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb(A23105,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells was used as blank control (red line). |
 | Flow cytometry:1×10^6 U-937 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb(A23105,5 μl/Test,right). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb(A23105,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 Human PBMC were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb(A23105,5 μl/Test,right). |
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