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ABflo® 488 Rabbit anti-Human MERTK mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | MER proto-oncogene, tyrosine kinase |
| Gene Symbol: | MERTK |
| Synonyms: | MER; RP38; c-Eyk; c-mer; Tyro12 |
| Gene ID: | 10461 |
| UniProt ID: | Q12866 |
| Clone ID: | 4D0C2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-499 of human MERTK (NP_006334.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-MERTK Antibody |
Background
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Images
 | Flow cytometry: 1×10^6 Hela cells (negative control,left) and 293T cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human MERTK mAb (A24727,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 293T cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human MERTK mAb (A24727,5 μl/Test,right). |
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