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ABflo® 488 Rabbit anti-Human MRC2 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | mannose receptor C-type 2 |
| Gene Symbol: | MRC2 |
| Synonyms: | CD280; UPARAP; CLEC13E; ENDO180 |
| Gene ID: | 9902 |
| UniProt ID: | Q9UBG0 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-513 of human MRC2 (NP_006030.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-MRC2 Antibody |
Background
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
Images
 | Flow cytometry: 1×10^6 Daudi cells (negative control,left) and U-138MG cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human MRC2 mAb (A26562,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 U-138MG cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Human MRC2 mAb (A26562,5 μl/Test,right). |
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