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| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | CD226 antigen |
| Gene Symbol: | Cd226 |
| Synonyms: | Pta1; DNAM1; DNAM-1; TLiSA1 |
| Gene ID: | 225825 |
| UniProt ID: | Q8K4F0 |
| Clone ID: | 4D5R2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-254 of mouse CD226/DNAM-1 (NP_848802.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cd226 antibody |
Background
Predicted to enable integrin binding activity and protein kinase binding activity. Acts upstream of or within positive regulation of interferon-gamma production and positive regulation of natural killer cell cytokine production. Located in external side of plasma membrane. Is expressed in embryo. Orthologous to human CD226 (CD226 molecule).
Images
![]() | Flow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Mouse CD226/DNAM-1 mAb (A25862,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 293T (Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD226/DNAM-1 mAb (A25862,5 μl/Test,right). |
![]() | Flow cytometry:1×10^6 C57BL/6 Splenocytes cells were surface-stained with ABflo® 647 Rabbit anti-Mouse CD8a mAb (A23904,5 μl/Test) and ABflo® 488 Rabbit anti-Mouse CD226/DNAM-1 mAb (A25862,5 μl/Test,left) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,right). |
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