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ABflo® 488 Rabbit anti-Mouse CD271/NGFR mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | nerve growth factor receptor (TNFR superfamily, member 16) |
| Gene Symbol: | Ngfr |
| Synonyms: | p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16 |
| Gene ID: | 18053 |
| UniProt ID: | Q9Z0W1 |
| Clone ID: | 8A4A3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-254 of mouse CD271 (NP_150086.2) . |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Ngfr antibody |
Background
Enables death receptor activity; nerve growth factor binding activity; and small GTPase binding activity. Involved in several processes, including cellular glucose homeostasis; circadian regulation of gene expression; and dorsal aorta development. Acts upstream of or within several processes, including hair follicle morphogenesis; nervous system development; and regulation of signal transduction. Located in several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor).
Images
 | Flow cytometry:1×10^6 293F cells (negative control,Left) and 293F(Transfection) cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD271/NGFR mAb(A24321,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 293F(Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD271/NGFR mAb(A24321,5 μl/Test,right) |
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