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ABflo® 488 Rabbit anti-Mouse CD31 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | platelet/endothelial cell adhesion molecule 1 |
| Gene Symbol: | Pecam1 |
| Synonyms: | Cd31; Pecam; PECAM-1 |
| Gene ID: | 18613 |
| UniProt ID: | Q08481 |
| Clone ID: | 4R9H3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-220 of mouse CD31 (NP_001292086.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Pecam1 antibody |
Background
Predicted to enable protein homodimerization activity; protein phosphatase binding activity; and transmembrane signaling receptor activity. Acts upstream of or within several processes, including Rho protein signal transduction; endothelial cell morphogenesis; and positive regulation of tyrosine phosphorylation of STAT protein. Located in several cellular components, including cell-cell contact zone; external side of plasma membrane; and smooth muscle contractile fiber. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in coronary artery disease (multiple); lung non-small cell carcinoma; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1).
Images
 | Flow cytometry:1×10^6 NIH/3T3 cells(negative control,left) and C57BL/6 mouse Splenocytes(right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD31 mAb(A23701,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 C57BL/6 mouse Splenocytes were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CD31 mAb(A23701,5 μl/Test,right). |
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