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ABflo® 488 Rabbit anti-Mouse CXCR2/IL-8RB mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | C-X-C motif chemokine receptor 2 |
| Gene Symbol: | Cxcr2 |
| Synonyms: | CD128; IL8RA; Il8rb; CDw128; Cmkar2; Gpcr16; IL-8Rh; IL-8rb; mIL-8RH |
| Gene ID: | 12765 |
| UniProt ID: | P35343 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-44 of mouse CXCR2/IL-8RB (NP_034039.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cxcr2 antibody |
Background
Enables chemokine receptor activity. Acts upstream of or within negative regulation of apoptotic process. Predicted to be located in several cellular components, including cell surface; mast cell granule; and mitotic spindle. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; epithelium; and heart. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; acute pyelonephritis; end stage renal disease; and urinary bladder cancer. Orthologous to human CXCR2 (C-X-C motif chemokine receptor 2).
Images
 | Flow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Mouse CXCR2/IL-8RB mAb (A26757,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 293T (Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse CXCR2/IL-8RB mAb (A26757,5 μl/Test,right). |
 | Flow cytometry: 1×10^6 RAW264.7 cells (negative control,left) and C57BL/6 mouse bone marrow cells (right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CXCR2/IL-8RB mAb (A26757,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
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