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ABflo® 488 Rabbit anti-Mouse ICOS/CD278 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | inducible T cell co-stimulator |
| Gene Symbol: | Icos |
| Synonyms: | H4; CCLP; AILIM; CRP-1; Ly115 |
| Gene ID: | 54167 |
| UniProt ID: | Q9WVS0 |
| Clone ID: | 1X6F9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-142 of mouse ICOS/CD278(NP_059508.2). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Icos antibody |
Background
Predicted to be involved in T cell costimulation; T cell tolerance induction; and cell-cell adhesion. Located in external side of plasma membrane. Is integral component of plasma membrane. Used to study common variable immunodeficiency. Human ortholog(s) of this gene implicated in celiac disease; common variable immunodeficiency; and immunoglobulin alpha deficiency. Orthologous to human ICOS (inducible T cell costimulator).
Images
 | Flow cytometry: 1×10^6 CHO cells(negative control,left) and CHO(Transfection,right) cells were surface-stained with ABflo® 488 Rabbit anti-Mouse ICOS/CD278 mAb(A23813,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 CHO(Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Mouse ICOS/CD278 mAb(A23813,5 μl/Test,right). |
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