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ABflo® 488 Rabbit anti-Rat ICAM-1/CD54 mAb (100 T)
| Reactivity: | Rat |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | intercellular adhesion molecule 1 |
| Gene Symbol: | Icam1 |
| Synonyms: | CD54; ICAM |
| Gene ID: | 25464 |
| UniProt ID: | Q00238 |
| Clone ID: | 7E3J3 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-493 of rat ICAM-1/CD54 (NP_037099.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Icam1 antibody |
Background
Enables integrin binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and gonad development. Located in cell surface; extracellular space; and plasma membrane. Used to study diabetic angiopathy; mesenteric vascular occlusion; nephritis; pre-eclampsia; and uveitis. Biomarker of several diseases, including cerebrovascular disease (multiple); colitis (multiple); kidney failure (multiple); lung disease (multiple); and pancreatitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); biliary atresia; diabetic retinopathy; inflammatory bowel disease (multiple); and liver cirrhosis. Orthologous to human ICAM1 (intercellular adhesion molecule 1).
Images
 | Flow cytometry: 1×10^6 293T cells (negative control,left) and Rat splenocytes (right) were surface-stained with ABflo® 488 Rabbit anti-Rat ICAM-1/CD54 mAb (A25834,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 Rat splenocytes were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 Rabbit anti-Rat ICAM-1/CD54 mAb (A25834,5 μl/Test,right). |
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