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ABflo® 488 anti-Mouse CD80 mAb (100 T)
| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Armenian Hamster |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 488. Ex:491nm. Em:516nm. |
| Gene Name: | CD80 antigen |
| Gene Symbol: | Cd80 |
| Synonyms: | B71; Ly53; TSA1; Cd28l; Ly-53; MIC17 |
| Gene ID: | 12519 |
| UniProt ID: | Q00609 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 38-245 of Mouse CD80. |
| Dilution: | FC, 5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.02 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Cd80 antibody |
Background
Predicted to enable coreceptor activity. Acts upstream of or within T cell costimulation; cellular response to lipopolysaccharide; and positive regulation of alpha-beta T cell proliferation. Located in external side of plasma membrane. Is expressed in heart ventricle and skin. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human CD80 (CD80 molecule).
Images
 | Flow cytometry: 1×10^6 P815 cells (negative control,left) and C2C12 cells (right) were surface-stained with ABflo® 488 anti-Mouse CD80 mAb (A26801,5 μl/Test,orange line) or ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 C2C12 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069,5 μl/Test,left) or ABflo® 488 anti-Mouse CD80 mAb (A26801,5 μl/Test,right). |
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