ABflo® 594 Rabbit anti-Human TREM1 mAb (100 T)

ABflo® 594 Rabbit anti-Human TREM1 mAb (100 T)

Brand: Abclonal
Cat. #: A26874
Availability: In Stock
$248.00
-+
Reactivity: Human    
Applications: FC    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Monoclonal Antibody    
Conjugation: ABflo® 594. Ex:588nm. Em:604nm.
Gene Name: triggering receptor expressed on myeloid cells 1
Gene Symbol: TREM1
Synonyms: CD354; TREM-1
Gene ID: 54210
UniProt ID: Q9NP99
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-200 of human TREM1 (NP_061113.1).
Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Purification Method: Affinity purification
Concentration: 0.04 mg/ml
Buffer: PBS with 0.03% proclin300,0.2% BSA, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-TREM1 antibody




Background

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.




Images

TREM1 antibodyFlow cytometry: 1×10^6 293T cells (negative control,left) and 293T (Transfection,right) cells were surface-stained with ABflo® 594 Rabbit anti-Human TREM1 mAb (A26874,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry: 1×10^6 Human PBMC were surface-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Human TREM1 mAb (A26874,5 μl/Test,right). Cells in the monocyte gate were used for analysis.



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