Reactivity: | Mouse |
Applications: | FC (intra) |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 594. Ex:588nm. Em:604nm. |
Gene Name: | interleukin 13 |
Gene Symbol: | Il13 |
Synonyms: | Il-13 |
Gene ID: | 16163 |
UniProt ID: | P20109 |
Clone ID: | 9Y10O4 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-131 of mouse IL-13 (NP_032381.1). |
Dilution: | FC (intra),5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.01 mg/mL |
Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-Il13 antibody |
Background
Predicted to enable interleukin-13 receptor binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of macrophage activation. Acts upstream of or within cellular response to cytokine stimulus; inflammatory response; and positive regulation of immune effector process. Located in cytoplasm; external side of plasma membrane; and extracellular space. Is expressed in gut; liver; male reproductive gland or organ; and thymus. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13).
Images
![]() | Flow cytometry: 1×10^6 CHO cells (negative control,left) and CHO (Transfection,right) cells were intracellularly-stained with ABflo® 594 Rabbit anti-Mouse IL-13 mAb (A25119,5 μl/Test,orange line) or ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
![]() | Flow cytometry: 1×10^6 CHO (Transfection) cells were intracellularly-stained with ABflo® 594 Rabbit IgG isotype control (A23821,5 μl/Test,left) or ABflo® 594 Rabbit anti-Mouse IL-13 mAb (A25119,5 μl/Test,right). |
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