Reactivity: | Human |
Applications: | FC |
Host Species: | Rabbit |
Isotype: | IgG |
Clonality: | Monoclonal Antibody |
Conjugation: | ABflo® 610. Ex:421nm. Em:612nm. |
Gene Name: | natural cytotoxicity triggering receptor 1 |
Gene Symbol: | NCR1 |
Synonyms: | LY94; CD335; NKP46; NK-p46 |
Gene ID: | 9437 |
UniProt ID: | O76036 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-254 of human CD335/NKp46 (NP_004820.2). |
Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
Purification Method: | Affinity purification |
Concentration: | 0.04 mg/ml |
Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
Documents: | Manual-NCR1 Antibody |
Background
Predicted to be involved in cellular defense response; regulation of natural killer cell mediated cytotoxicity; and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome.
Images
![]() | Flow cytometry:1×10^6 Human PBMC were surface-stained with FITC Rabbit anti-Human CD56 mAb (5 μl/Test) and ABflo® 610 Rabbit IgG isotype control (A25826,5 μl/Test,left) or ABflo® 610 Rabbit anti-Human CD335/NKp46 mAb(A27141,5 μl/Test,right). Cells in the lymphocyte gate were used for analysis. |
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