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ABflo® 647 Rabbit anti-Human CD213a1/IL-13Rα1 mAb (100 T)
| Reactivity: | Human |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | ABflo® 647. Ex:648nm. Em:664nm. |
| Gene Name: | interleukin 13 receptor subunit alpha 1 |
| Gene Symbol: | IL13RA1 |
| Synonyms: | NR4; CT19; CD213A1; IL-13Ra |
| Gene ID: | 3597 |
| UniProt ID: | P78552 |
| Clone ID: | 4O2Y6 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-343 of human CD213a1/IL-13Rα1 (NP_001551.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.01 mg/mL |
| Buffer: | PBS with 0.03% proclin300,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-IL13RA1 Antibody |
Background
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Images
 | Flow cytometry: 1×10^6 Jurkat cells (negative control,left) and MCF7 cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human CD213a1/IL-13Rα1 mAb(A24284,5 μl/Test,orange line) or ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,blue line).Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry:1×10^6 MCF7 cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070,5 μl/Test,left) or ABflo® 647 Rabbit anti-Human CD213a1/IL-13Rα1 mAb(A24284,5 μl/Test,right). |
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